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people at higher risk of deficiency include older adults, those with gastrointestinal issues that impair absorption, people whove had gastric surgery, long-term strict vegans who do not supplement, and those on certain acid-reducing medicines

Those with certain digestive conditions, such as Crohns disease, may also see improvements if their deficiency stems from absorption problems

It is a research compound with preclinical data only -- no human clinical trials have been published

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